Do I control my life or is everything pre-dermined. I believe it is not an either/or answer. I think it is both. Destiny gives a set of range of values. My effort determines which value I end up with. So this sequence keeps repeating.
Can "I" determine where I get born? - No. Can I determine my set of genes? Can I determine which diseases I don't want to have? On many major things in life I don't have much influence. I can always choose to put in the effort to choose more desirable of the alternatives or just think everything is destiny and give up.
Accepting what is there and trying to make the best out of it is a better way to live a happy life.